The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 14, 2025

Filed:

Jul. 08, 2021
Applicant:

Shenzhen University, Guangdong, CN;

Inventors:

Suping Zhang, Guangdong, CN;

Thomas James Kipps, Guangdong, CN;

Liufeng Wu, Guangdong, CN;

Jianchao Zhang, Guangdong, CN;

Assignee:

SHENZHEN UNIVERSITY, Shenzhen, CN;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 16/28 (2006.01); A61K 39/00 (2006.01); C07K 14/705 (2006.01); C07K 14/725 (2006.01); G01N 33/68 (2006.01);
U.S. Cl.
CPC ...
C07K 16/2803 (2013.01); C07K 14/7051 (2013.01); C07K 14/70517 (2013.01); C07K 14/70578 (2013.01); G01N 33/68 (2013.01); A61K 2039/505 (2013.01); C07K 2317/24 (2013.01); C07K 2317/622 (2013.01); C07K 2317/732 (2013.01); C07K 2319/03 (2013.01); G01N 2333/70503 (2013.01);
Abstract

Disclosed are an anti-ROR2 antibody and a use thereof. The anti-ROR2 antibody includes at least one of the following: (1) a light chain variable region with amino acid sequence shown in SEQ ID NO: 1, SEQ ID NO: 2 and SEQ ID NO: 3, and a heavy chain variable region with amino acid sequence shown in SEQ ID NO: 4, SEQ ID NO: 5 and SEQ ID NO: 6; compared with (1), the antibody or antigen-binding fragment has an amino acid sequence with at least one conservative amino acid substitution.


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