The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 14, 2025
Filed:
Aug. 29, 2022
Dana-farber Cancer Institute, Inc., Boston, MA (US);
President and Fellows of Harvard College, Cambridge, MA (US);
Rosalind Segal, Brookline, MA (US);
Loren D. Walensky, Newton, MA (US);
Lisa V. Goodrich, Newton, MA (US);
Sarah Elizabeth Raissi, Waltham, MA (US);
Maria F. Murphy, Revere, MA (US);
Gregory H. Bird, Pelham, NH (US);
Dana-Farber Cancer Institute, Inc., Boston, MA (US);
President and Fellows of Harvard College, Cambridge, MA (US);
Abstract
Compositions and methods are provided for the treatment or prevention of chemotherapy-induced peripheral neuropathy and hearing loss in a subject in need thereof. The methods involve administering to the subject a bclw protein, a BH4 domain-containing fragment thereof, or a bclw mimetic. Also provided are exemplary bclw mimetics.