The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 14, 2025

Filed:

Nov. 22, 2024
Applicant:

Wuhan University, Hubei, CN;

Inventors:

Yuhui Sun, Hubei, CN;

Minghe Luo, Hubei, CN;

Yanqin Li, Hubei, CN;

Jin Xiang, Hubei, CN;

Zixin Deng, Hubei, CN;

Assignee:

WUHAN UNIVERSITY, Hubei, CN;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 5/103 (2006.01); A61K 38/00 (2006.01); A61P 1/16 (2006.01); A61P 25/04 (2006.01); A61P 25/36 (2006.01); A61P 29/00 (2006.01); A61P 35/00 (2006.01); C07K 1/20 (2006.01); C12P 21/02 (2006.01); C12R 1/465 (2006.01);
U.S. Cl.
CPC ...
C07K 5/1008 (2013.01); A61P 1/16 (2018.01); A61P 25/04 (2018.01); A61P 25/36 (2018.01); A61P 29/00 (2018.01); A61P 35/00 (2018.01); C07K 1/20 (2013.01); C12P 21/02 (2013.01); A61K 38/00 (2013.01); C12R 2001/465 (2021.05);
Abstract

The embodiment of the present invention discloses Hangtaimycin derivatives and their preparation and application. Hangtaimycin derivatives are obtained by fermentation ofCCTCC M2017417 and its genetically knockout mutant strain in SFMR medium, with further isolation, purification, and alcoholysis. Through screening, Hangtaimycin derivatives showed excellent anti-inflammatory and analgesic, anti-tumor, liver injury protection, cell membrane protection, and drug addiction prevention activities, providing new drug leads for developing related drugs.


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