The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 14, 2025
Filed:
Jun. 05, 2020
Applicant:
University of Massachusetts, Boston, MA (US);
Inventors:
Celia A. Schiffer, Shrewsbury, MA (US);
Akbar Ali, Westborough, MA (US);
Jacqueto Zephyr, Worcester, MA (US);
Ashley N. Matthew, Worcester, MA (US);
Nageswara R. Desaboini, Worcester, MA (US);
Assignee:
University of Massachusetts, Westborough, MA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 5/083 (2006.01); A61K 38/00 (2006.01); C07K 5/107 (2006.01);
U.S. Cl.
CPC ...
C07K 5/0804 (2013.01); C07K 5/1016 (2013.01); A61K 38/00 (2013.01);
Abstract
The invention provides novel classes of HCV therapeutics that are orally available, safe and effective HCV NS3/4A protease inhibitors and are less susceptible to drug resistance than existing therapeutics. The invention also relates to pharmaceutical composition of these compounds and methods of preparation and use thereof.