The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 14, 2025
Filed:
Dec. 17, 2020
The George Washington University, Washington, DC (US);
University of Utah Research Foundation, Salt Lake City, UT (US);
Alberto Bosque-Pardos, Washington, DC (US);
Amanda Beatriz Rodrigues Barreto De Macedo, Washington, DC (US);
Eric S. Sorensen, Washington, DC (US);
Vicente Planelles, Salt Lake City, UT (US);
The George Washington University, Washington, DC (US);
University of Utah Research Foundation, Salt Lake City, UT (US);
Abstract
The present disclosure generally relates to compositions and methods for ex vivo expansion of immune cells isolated from a subject, wherein gene expression can be modulated to enhance immune cell activity in the resulting expanded immune cell culture. Modulation of gene expression in an expanded immune cell culture allows for an immune cell therapy contains genetically chemically modified immune cells suitable for the adoptive cell transfer into a subject in need thereof.