The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 14, 2025

Filed:

Nov. 12, 2020
Applicant:

Vifor (International) Ltd., St. Gallen, CH;

Inventors:

Qingwu Jin, Bothell, WA (US);

Michael Whitacre, San Carlos, CA (US);

Assignee:

VIFOR (INTERNATIONAL) LTD., St. Gallen, CH;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07C 67/32 (2006.01); C08F 220/22 (2006.01); C08J 3/09 (2006.01);
U.S. Cl.
CPC ...
C07C 67/32 (2013.01); C08F 220/22 (2013.01); C08J 3/095 (2013.01); C08J 2333/16 (2013.01);
Abstract

A process is provided that results in an alkyl haloacrylate that is produced by reaction of a dialkyl or diaryl halomalonate with an aldehyde, preferably formalin or paraformaldehyde, and a base catalyst to produce an intermediate that is not isolated and is heated to produce the alkyl haloacrylate. This synthesis can be one pot, meaning it reacts in the same vessel and/or reaction mixture and does not require isolation of the intermediate, and provides an improved yield. In particular, a process is provided that results in an alkyl 2-fluoroacrylate.


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