The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 14, 2025

Filed:

Feb. 11, 2022
Applicant:

Thermolife International, Llc, Signal Hill, CA (US);

Inventors:

Ronald Kramer, Signal Hill, CA (US);

Alexandros Nikolaidis, Nea Kallikratia, GR;

Assignee:

ThermoLife International, LLC, Signal Hill, CA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 33/00 (2006.01); A61K 9/00 (2006.01); A61K 33/06 (2006.01); A61M 16/10 (2006.01); A61M 16/12 (2006.01); A61P 11/00 (2006.01); A61P 11/08 (2006.01); C01B 21/24 (2006.01);
U.S. Cl.
CPC ...
C01B 21/24 (2013.01); A61K 9/007 (2013.01); A61K 33/00 (2013.01); A61M 16/10 (2013.01); A61M 16/12 (2013.01); A61P 11/00 (2018.01); A61P 11/08 (2018.01); A61M 2202/0275 (2013.01);
Abstract

The disclosure relates to methods of producing nitric oxide (NO) gas that is administrable without specialized equipment and does not provide nitrogen dioxide (NO) gas. The methods comprise combining a nitrate and/or nitrite anion and an elemental metal in an acidic solution in a vessel capable of housing liquid and gas constituents, wherein NO gas is produced by the reaction of the nitrate and/or nitrite anion and the elemental metal in the acidic solution. The method further comprises administering the NO gas produced to the subject via inhalation. Also described are compositions and kits for improved delivery of NO gas.


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