The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 14, 2025

Filed:

Dec. 22, 2021
Applicant:

City of Hope, Duarte, CA (US);

Inventors:

Markus Kalkum, Duarte, CA (US);

Daniel Roeth, Duarte, CA (US);

Isaac Bishara, Duarte, CA (US);

Miro Rusnak, Duarte, CA (US);

Sanjeet Dadwal, Duarte, CA (US);

Assignee:

City of Hope, Duarte, CA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
B01L 3/00 (2006.01); C12Q 1/6806 (2018.01); G01K 3/00 (2006.01); G01N 21/64 (2006.01); G06V 10/56 (2022.01); G06V 20/69 (2022.01);
U.S. Cl.
CPC ...
B01L 3/508 (2013.01); C12Q 1/6806 (2013.01); G01K 3/005 (2013.01); G01N 21/6428 (2013.01); G01N 21/6456 (2013.01); G06V 10/56 (2022.01); G06V 20/693 (2022.01); B01L 2200/10 (2013.01); B01L 2200/147 (2013.01); B01L 2200/16 (2013.01); B01L 2200/18 (2013.01); B01L 2300/046 (2013.01); B01L 2300/0681 (2013.01); B01L 2300/1827 (2013.01); G01N 2201/062 (2013.01);
Abstract

Provided are methods, devices, and systems for a loop-mediated isothermal amplification (LAMP) reactions for detecting the presence of genetic material. A LAMP device includes an enclosure having outer walls configured to define an internal space. The LAMP device also includes a tray assembly configured to support a reaction vessel configured for holding a sample for amplification. The LAMP device also includes a plurality of light emitters configured to illuminate the reaction vessel for exciting a fluorescence of the sample in the reaction vessel. The LAMP device also includes an imaging device configured to obtain an image of the sample for determining a quantity of the fluorescence in the sample. The LAMP device also includes a controller configured to regulate a temperature of the tray assembly and instruct the imaging device to obtain the image for determining the quantity of the fluorescence in the sample.


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