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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 12440576 B1

PDFFull Text
Date of Patent:
Oct. 14, 2025

Filed:

Dec. 19, 2022

Antibody drug conjugates comprising sting agonists

Applicant:

Mersana Therapeutics, Inc., Cambridge, MA (US);

Inventors:

Jeremy R. Duvall, Topsfield, MA (US);

Keith W. Bentley, Boston, MA (US);

Raghida A. Bukhalid, Medford, MA (US);

Naniye Cetinbas, Somerville, MA (US);

Marc I. Damelin, Needham, MA (US);

Eugene W. Kelleher, Wellesley, MA (US);

Timothy B. Lowinger, Carlisle, MA (US);

Joshua D. Thomas, Natick, MA (US);

Dorin Toader, Cambridge, MA (US);

Ling Xu, Brookline, MA (US);

Liping Yang, Arlington, MA (US);

Assignee:

Mersana Therapeutics, Inc., Cambridge, MA (US);

Attorney:

Fenwick & West LLP

Primary Examiner:

Karen A Canella

Assistant Examiner:

John J Skoko, Iii

Int. Cl.
CPC ...
A61K 47/68 (2017.01); A61K 31/4184 (2006.01); A61K 31/422 (2006.01); A61K 31/428 (2006.01); A61K 31/437 (2006.01); A61K 45/06 (2006.01); A61K 47/54 (2017.01); A61K 47/55 (2017.01); A61K 47/60 (2017.01); A61K 47/65 (2017.01); A61P 35/00 (2006.01);
U.S. Cl.
CPC ...
A61K 47/6849 (2017.08); A61K 31/4184 (2013.01); A61K 31/422 (2013.01); A61K 31/428 (2013.01); A61K 31/437 (2013.01); A61K 45/06 (2013.01); A61K 47/54 (2017.08); A61K 47/542 (2017.08); A61K 47/545 (2017.08); A61K 47/55 (2017.08); A61K 47/60 (2017.08); A61K 47/65 (2017.08); A61K 47/6803 (2017.08); A61K 47/6841 (2017.08); A61P 35/00 (2018.01);
Abstract

The present disclosure provides scaffolds and antibody-drug conjugates (ADCs) comprising a stimulator of interferon genes (STING). The present disclosure also provides uses of the ADCs in treatment, e.g., treatment of cancer.

Find Patent Forward Citations

Duvall, Jeremy. (2025). Antibody drug conjugates comprising sting agonists (U.S. Patent No. 12440576). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/12440576

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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