The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 14, 2025
Filed:
May. 16, 2019
Zhengzhou Gensciences Inc., Henan, CN;
Hongsheng Su, Beijing, CN;
Xiaoshan Wang, Beijing, CN;
Bin Liu, Beijing, CN;
Xian Chen, Beijing, CN;
Xiang Li, Beijing, CN;
Luyan Zhu, Beijing, CN;
Shuya Wang, Kaifeng, CN;
Shuang Wang, Beijing, CN;
Wenwen Wang, Kaifeng, CN;
Lingli Huang, Kaifeng, CN;
Qilei Wang, Kaifeng, CN;
Haitao Hu, Kaifeng, CN;
Lili Zhang, Kaifeng, CN;
Jie Gao, Kaifeng, CN;
Zijia Ren, Kaifeng, CN;
Chunfeng Xiao, Beijing, CN;
Yali Wang, Beijing, CN;
ZHENGZHOU GENSCIENCES INC., Zhengzhou, CN;
Abstract
Disclosed are a coagulation factor VIII fusion protein which is conjugated with polyalkylene glycol and which has an extended cyclic half-life, a preparation method therefor and a use thereof, wherein the active moiety of the coagulation factor VIII is directly linked or indirectly linked by a peptide linker to a fusion partner, and the fusion protein is further conjugated to a polyalkylene glycol. The half-life is significantly increased compared to an FVIII fusion protein modified without polyalkylene glycol.