The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 14, 2025

Filed:

Dec. 07, 2020
Applicants:

Shenzhen University, Guangdong, CN;

Shenzhen Conjugenix Pharmaceutical Technology Company Limited, Guangdong, CN;

Inventors:

Guangyi Jin, Guangdong, CN;

Zhulin Wang, Guangdong, CN;

Ji Zhou, Guangdong, CN;

Mian Qin, Guangdong, CN;

Sumei Ren, Guangdong, CN;

Yajuan Cheng, Guangdong, CN;

Shuxian Tan, Guangdong, CN;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 47/55 (2017.01); A61K 47/62 (2017.01); A61P 37/04 (2006.01); C07D 487/04 (2006.01); C07D 519/00 (2006.01); C07F 9/6561 (2006.01); C07F 9/6584 (2006.01);
U.S. Cl.
CPC ...
A61K 47/55 (2017.08); A61K 47/62 (2017.08); A61P 37/04 (2018.01); C07D 487/04 (2013.01); C07D 519/00 (2013.01); C07F 9/65616 (2013.01); C07F 9/65846 (2013.01);
Abstract

The present application provides a novel series of small molecular immune agonists of Toll-like receptor, having a structure represented by Formula I. The present application further provides use of the immune agonist for activating and amplifying immune cells and lymphocytes, and for preparing an immunomodulatory drug, an immune anti-tumor small molecule drug, and an immune anti-tumor macromolecular drug.


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