The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 14, 2025
Filed:
May. 31, 2024
Applicant:
Ottawa Hospital Research Institute, Ottawa, CA;
Inventors:
Jean-Simon Diallo, Ottawa, CA;
Mohammed Selman, Ann Arbor, MI (US);
Rozanne Arulanandam, Orleans, CA;
Nicole Elise Forbes, Ottawa, CA;
Ramya Krishnan, Ottawa, CA;
Assignee:
OTTAWA HOSPITAL RESEARCH INSTITUTE, Ottawa, CA;
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12N 7/00 (2006.01); A61K 31/225 (2006.01); A61K 35/766 (2015.01); A61P 35/00 (2006.01); C07C 69/60 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
A61K 35/766 (2013.01); A61K 31/225 (2013.01); A61P 35/00 (2018.01); C07C 69/60 (2013.01); C12N 7/00 (2013.01); A61K 2039/585 (2013.01); C12N 2710/10332 (2013.01); C12N 2710/10351 (2013.01); C12N 2740/16134 (2013.01); C12N 2760/16134 (2013.01); C12N 2760/16151 (2013.01); C12N 2760/20232 (2013.01); C12N 2760/20251 (2013.01);
Abstract
Provided herein are fumaric-containing compounds, compositions comprising the same and methods for using such compounds for increasing the capacity of an interferon-sensitive virus to infect, transduce, grow or replicate in a cell or spread within one or more tissues. Also provided are methods for increasing the capacity of an interferon-sensitive virus to produce a virus-encoded transgene from a cell, by administering the compounds and compositions.