The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 14, 2025

Filed:

Aug. 01, 2019
Applicant:

The Trustees of Columbia University IN the City of New York, New York, NY (US);

Inventors:

Konstantin Petrukhin, New Windsor, NY (US);

Boglarka Racz, Brooklyn, NY (US);

Andras Varadi, Brooklyn, NY (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/4545 (2006.01); A61K 31/506 (2006.01); A61P 1/16 (2006.01); A61P 19/06 (2006.01);
U.S. Cl.
CPC ...
A61K 31/4545 (2013.01); A61K 31/506 (2013.01); A61P 1/16 (2018.01); A61P 19/06 (2018.01);
Abstract

The subject invention provides a method for treating a non-alcoholic fatty liver disease (NAFLD) disease in a subject afflicted therewith comprising administering to the subject a pharmaceutical composition comprising an amount of a compound which is a non-retinoid retinol-binding protein 4 (RBP4) antagonist effective to treat the subject, thereby treating the subject. The subject invention provides a method for treating gout in a subject afflicted therewith comprising administering to the subject a pharmaceutical composition comprising an amount of a compound which is a retinol-binding protein 4 (RBP4) antagonist effective to treat the subject, thereby treating the subject.


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