The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 14, 2025

Filed:

Oct. 01, 2021
Applicant:

American Regent, Inc., Shirley, NY (US);

Inventors:

Daniel Walter Wehrung, Johnstown, OH (US);

Meng Zhong, Westerville, OH (US);

Saral Pinkal Patel, Powell, OH (US);

Bindhu Madhavi Rayaprolu, Columbus, OH (US);

Assignee:

American Regent, Inc., Shirley, NY (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/4422 (2006.01); A61K 47/18 (2017.01);
U.S. Cl.
CPC ...
A61K 31/4422 (2013.01); A61K 47/183 (2013.01);
Abstract

Provided herein are pharmaceutical compositions comprising a class of calcium channel blockers and at least one chelating agent. More specifically, the pharmaceutical compositions comprise at least one 1,4-dihydropyridine (DHP) compound and at least one chelating agent. The chelating agents used in this disclosure can decrease the degradation of the constituent DHPs of the DHP compositions. The DHP compositions can be used to treat cardiovascular disorders and are more stable for prolonged periods of time.


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