The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 14, 2025

Filed:

Aug. 28, 2020
Applicant:

Syddansk Universitet, Odense M, DK;

Inventor:

Tore Bjerregaard Stage, Odense SV, DK;

Assignee:

Syddansk Universitet, Odense M, DK;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/337 (2006.01); A61K 9/00 (2006.01); A61K 31/475 (2006.01); A61K 31/55 (2006.01); A61K 31/57 (2006.01); A61P 17/14 (2006.01); A61P 25/02 (2006.01); A61P 35/00 (2006.01);
U.S. Cl.
CPC ...
A61K 31/337 (2013.01); A61K 9/0014 (2013.01); A61K 31/475 (2013.01); A61K 31/55 (2013.01); A61K 31/57 (2013.01); A61P 17/14 (2018.01); A61P 25/02 (2018.01); A61P 35/00 (2018.01);
Abstract

The present invention relates to compositions comprising a P-gp inducer, for topical use in preventing one or more side effects of chemotherapeutics, which chemotherapeutics are transported out of cells by P-gp. Especially chemotherapy-induced peripheral neuropathy (CIPN) is a relevant side effect to treat/avoid, since CIPN may be a dose limiting side effect of chemotherapy. The invention also relates to kits and to cancer treatment of a subgroup of patients, which subgroup has been topically pretreated with a P-gp inducer.


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