The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 14, 2025
Filed:
Sep. 07, 2023
Applicant:
North Carolina State University, Raleigh, NC (US);
Inventors:
Ismaeel Muhamed, Raleigh, NC (US);
Ashley C. Brown, Raleigh, NC (US);
Frances S. Ligler, Raleigh, NC (US);
Assignee:
North Carolina State University, Raleigh, NC (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/14 (2006.01); A61K 9/50 (2006.01); A61K 45/06 (2006.01); A61K 47/69 (2017.01); A61P 17/02 (2006.01);
U.S. Cl.
CPC ...
A61K 9/5052 (2013.01); A61K 9/5089 (2013.01); A61K 45/06 (2013.01); A61K 47/6925 (2017.08); A61P 17/02 (2018.01);
Abstract
Disclosed herein are low density particles comprising polymerized fibrin that are micrometer or nanometer sized in diameter. The particles can further include at least one therapeutic agent. The particles may be used to treat wounds, by administration directly or systemically to the site of the wound. Exemplary wounds that may be treated with the fibrin particles include a trauma wound, a surgical wound, a burn wound, or an ulcer wound. Also disclosed herein are methods for preparing the particles using a shearing process.