The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 07, 2025
Filed:
Jul. 07, 2022
Applicant:
The Regents of the University of California, Oakland, CA (US);
Inventors:
Jeffrey A. Bluestone, San Francisco, CA (US);
Weihong Liu, San Francisco, CA (US);
Amy Putnam, San Francisco, CA (US);
Assignee:
The Regents of the University of California, Oakland, CA (US);
Primary Examiner:
Int. Cl.
CPC ...
A61K 40/11 (2025.01); A61K 39/00 (2006.01); A61K 40/22 (2025.01); A61K 40/41 (2025.01); C12N 5/0783 (2010.01); G01N 33/50 (2006.01); G01N 33/569 (2006.01); A61K 35/12 (2015.01);
U.S. Cl.
CPC ...
G01N 33/56972 (2013.01); A61K 39/0008 (2013.01); A61K 40/11 (2025.01); A61K 40/22 (2025.01); A61K 40/416 (2025.01); C12N 5/0636 (2013.01); G01N 33/505 (2013.01); A61K 2035/122 (2013.01); A61K 2039/515 (2013.01); G01N 2333/70514 (2013.01); G01N 2333/70517 (2013.01); G01N 2333/70596 (2013.01); G01N 2333/7155 (2013.01);
Abstract
The invention provides methods of isolating CD 127immunosuppressive regulatory T cells which can be greatly enriched for FoxP3, methods of expanding the isolated cells, pharmaceutical compositions of such cells, and methods of their use in the treatment of autoimmune and other immune system mediated disorders.