The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 07, 2025
Filed:
Aug. 11, 2021
Applicant:
The University of Chicago, Chicago, IL (US);
Inventor:
Y. Lynn Wang, Chicago, IL (US);
Assignee:
The University of Chicago, Chicago, IL (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/68 (2018.01); C12N 9/12 (2006.01); C12Q 1/6886 (2018.01); G01N 33/573 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/6886 (2013.01); C12N 9/12 (2013.01); G01N 33/573 (2013.01); C12Q 2600/106 (2013.01); C12Q 2600/156 (2013.01); G01N 2333/912 (2013.01); G01N 2800/52 (2013.01);
Abstract
Provided herein are mutations in Bruton's Tyrosine Kinase (BTK) that confer resistance to treatment with a BTK inhibitors, such as Ibrutinib, and compositions and methods for the treatment, diagnosis, and characterization of BTK-inhibitor-resistant cancers.