The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 07, 2025
Filed:
Jul. 06, 2018
Nipd Genetics Public Company Limited, Nicosia, CY;
George Koumbaris, Lithrodontas, CY;
Marios Ioannides, Nicosia, CY;
Elena Kypri, Nicosia, CY;
Acilleas Achilleos, Limassol, CY;
Petros Mina, Nicosia, CY;
Alexia Eliades, Nicosia, CY;
Charalambos Loizides, Nicosia, CY;
Philippos Patsalis, Nicosia, CY;
NIPD GENETICS PUBLIC COMPANY LIMITED, Nicosia, CY;
Abstract
The invention provides methods for assessment of tumor biomarkers using target-enriched multiplexed parallel analysis. The methods of the invention utilize Target Capture Sequences (TACS) to thereby enrich for target sequences of interest, followed by massive parallel sequencing and statistical analysis of the enriched population. The methods can be used with DNA samples from a patient, such as a tissue biopsy or plasma sample (liquid biopsy), for detection of the presence of tumor biomarkers, e.g., for purposes of diagnosis, screening, therapy selection and/or treatment monitoring. Kits for carrying out the methods of the invention are also provided.