The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 07, 2025

Filed:

Aug. 13, 2019
Applicants:

Illumina, Inc., San Diego, CA (US);

Illumina Cambridge Limited, Cambridge, GB;

Inventors:

Andrew F. Slatter, Cambridge, GB;

Junhua Zhao, San Diego, CA (US);

Grace Desantis, San Diego, CA (US);

Stephen M. Gross, San Diego, CA (US);

Hayley Marianne Hogan, San Diego, CA (US);

Jian-Sen Li, San Diego, CA (US);

Oliver Jon Miller, Cambridge, GB;

Assignees:

Illumina, Inc., San Diego, CA (US);

Illumina Cambridge Limited, Cambridge, GB;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/6832 (2018.01); C12Q 1/6869 (2018.01);
U.S. Cl.
CPC ...
C12Q 1/6832 (2013.01); C12Q 1/6869 (2013.01);
Abstract

This disclosure describes a hybridization buffer including a crowding agent, a method that includes using the hybridization buffer, and a kit including the hybridization buffer. This disclosure also describes blockers for use in hybrid capture methods, methods of using those blockers, and a kit including those blockers. Additionally, this disclosure describes a method of hybrid capture that does not include amplifying the library members using PCR prior to sequencing the library members.


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