The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 07, 2025
Filed:
Feb. 27, 2023
Applicant:
Brown University, Providence, RI (US);
Inventors:
Jeffrey R. Morgan, Sharon, MA (US);
Benjamin T. Wilks, Boston, MA (US);
Assignee:
Brown University, Providence, RI (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 5/077 (2010.01);
U.S. Cl.
CPC ...
C12N 5/0656 (2013.01); C12N 2501/15 (2013.01); C12N 2501/727 (2013.01); C12N 2503/02 (2013.01); C12N 2513/00 (2013.01); C12N 2527/00 (2013.01); C12N 2533/76 (2013.01);
Abstract
Described herein are in vitro quantitative methods directed to 3D extracellular matrix (ECM) organization and mechanics. The methods do not require application of an external force, anchorage, or a scaffolding material in order to culture ECM tissue constructs, and the methods enable quantitative measurements without crosstalk noise from variables attributable to external forces, anchorage, and scaffolding material.