The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 07, 2025

Filed:

Nov. 19, 2021
Applicant:

Zymeworks Bc Inc., Vancouver, CA;

Inventors:

Diana F. Hausman, Seattle, WA (US);

Neil C. Josephson, Seattle, WA (US);

Rose Kamyee Lai, Seattle, WA (US);

Gerald James Rowse, Vancouver, CA;

Patrick Kaminker, Seattle, WA (US);

Assignee:

ZYMEWORKS BC INC., Vancouver, CA;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 16/32 (2006.01); A61K 31/7068 (2006.01); A61K 33/243 (2019.01); A61K 39/00 (2006.01); A61K 47/54 (2017.01); A61K 47/68 (2017.01);
U.S. Cl.
CPC ...
C07K 16/32 (2013.01); A61K 31/7068 (2013.01); A61K 33/243 (2019.01); A61K 47/545 (2017.08); A61K 47/68031 (2023.08); A61K 47/6817 (2017.08); A61K 47/6851 (2017.08); A61K 39/00 (2013.01); C07K 2317/51 (2013.01); C07K 2317/515 (2013.01);
Abstract

Described herein is a method of treating biliary tract cancer (BTC) comprising administering a bispecific antigen-binding construct targeting HER2 or a bispecific antigen-binding construct targeting HER2 linked to an auristatin analogue (ADC) to a subject.


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