The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 07, 2025

Filed:

Jun. 20, 2018
Applicant:

Amgen Inc., Thousand Oaks, CA (US);

Inventors:

Darren L Bates, Oak Park, CA (US);

Donghui Shi, Thousand Oaks, CA (US);

David J. Lloyd, Thousand Oaks, CA (US);

Pavel Bondarenko, Thousand Oaks, CA (US);

Mark L Michaels, Encino, CA (US);

Todd Hager, Agoura Hills, CA (US);

Xiaoshan Min, Burlingame, CA (US);

Aiko Umeda, Woodland Hills, CA (US);

Irwin Chen, Los Angeles, CA (US);

Zhulun Wang, Palo Alto, CA (US);

Assignee:

AMGEN INC., Thousand Oaks, CA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 16/28 (2006.01); A61K 9/00 (2006.01); A61K 38/26 (2006.01);
U.S. Cl.
CPC ...
C07K 16/2869 (2013.01); A61K 38/26 (2013.01); A61K 9/0019 (2013.01); C07K 2317/21 (2013.01); C07K 2317/54 (2013.01); C07K 2317/55 (2013.01);
Abstract

Methods of treating metabolic diseases and disorders using an antigen binding protein specific for the GIPR polypeptide are provided. In various embodiments the metabolic disease or disorder is type 2 diabetes, obesity, dyslipidemia, elevated glucose levels, elevated insulin levels and diabetic nephropathy. In certain embodiments the antigen binding protein is administered in combination with a GLP-1 receptor agonist.


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