The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 07, 2025
Filed:
Jul. 22, 2022
Applicant:
A2 Biotherapeutics, Inc., Agoura Hills, CA (US);
Inventors:
Xueyin Wang, Agoura Hills, CA (US);
Carl Alexander Kamb, Agoura Hills, CA (US);
Han Xu, Agoura Hills, CA (US);
Mark L. Sandberg, Agoura Hills, CA (US);
Dora Toledo Warshaviak, Agoura Hills, CA (US);
Assignee:
A2 Biotherapeutics, Inc., Agoura Hills, CA (US);
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/705 (2006.01); A61K 39/00 (2006.01); A61K 40/11 (2025.01); A61K 40/31 (2025.01); A61K 40/32 (2025.01); A61K 40/42 (2025.01); A61P 35/00 (2006.01); C07K 14/725 (2006.01);
U.S. Cl.
CPC ...
C07K 14/70578 (2013.01); A61K 40/11 (2025.01); A61K 40/31 (2025.01); A61K 40/32 (2025.01); A61K 40/4266 (2025.01); A61P 35/00 (2018.01); C07K 14/7051 (2013.01); C07K 14/70517 (2013.01); C07K 14/70521 (2013.01); A61K 2239/50 (2023.05);
Abstract
The disclosure provides immune cells comprising a first activator receptor specific to CEA, and a second inhibitory receptor, and methods of making and using same for the treatment of cancer.