The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 07, 2025

Filed:

Jun. 21, 2022
Applicant:

Gc Cell Corporation, Yongin-si, KR;

Inventors:

Yu Kyeong Hwang, Yongin-si, KR;

Sung Yoo Cho, Yongin-si, KR;

Sung Yong Won, Yongin-si, KR;

Ho Yong Lim, Yongin-si, KR;

Jung Hyun Her, Yongin-si, KR;

Mi Young Jung, Yongin-si, KR;

Hyun Ah Kim, Yongin-si, KR;

Su Hyun Gwon, Yongin-si, KR;

Eun Sol Lee, Yongin-si, KR;

Han Sol Kim, Yongin-si, KR;

Assignee:

GC Cell Corporation, Gyeonggi-do, KR;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/725 (2006.01); A61K 40/15 (2025.01); A61K 40/31 (2025.01); A61K 40/42 (2025.01); C07K 16/28 (2006.01); C12N 5/0783 (2010.01);
U.S. Cl.
CPC ...
C07K 14/7051 (2013.01); A61K 40/15 (2025.01); A61K 40/31 (2025.01); A61K 40/4221 (2025.01); A61K 40/4224 (2025.01); C07K 16/2815 (2013.01); C07K 16/2818 (2013.01); C07K 16/283 (2013.01); C07K 16/2851 (2013.01); C12N 5/0646 (2013.01); A61K 2239/22 (2023.05); A61K 2239/48 (2023.05); A61K 2239/49 (2023.05); A61K 2239/55 (2023.05); C07K 2317/622 (2013.01); C07K 2317/73 (2013.01); C07K 2319/03 (2013.01); C07K 2319/33 (2013.01);
Abstract

The present invention provides a chimeric antigen receptor and natural killer cells expressing the same, and particularly, a chimeric antigen receptor (CAR) which includes an intracellular signaling domain including the whole or a portion of an OX40 ligand (CD252), thereby having excellent effects of increasing anticancer activity of immune cells, and immune cells expressing the same.


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