The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 07, 2025
Filed:
Sep. 17, 2019
Applicant:
Erasmus University Medical Center Rotterdam, Rotterdam, NL;
Inventor:
Jeroen De Vrij, Leidschendam, NL;
Assignee:
Erasmus University Medical Center Rotterdam, Rotterdam, NL;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 35/761 (2015.01); C07K 14/005 (2006.01); C12N 15/86 (2006.01); C12N 15/88 (2006.01);
U.S. Cl.
CPC ...
C07K 14/005 (2013.01); A61K 35/761 (2013.01); C12N 15/86 (2013.01); C12N 15/88 (2013.01); C07K 2319/60 (2013.01); C12N 2710/10322 (2013.01); C12N 2710/10332 (2013.01); C12N 2710/10343 (2013.01); C12N 2710/10345 (2013.01); C12N 2710/10362 (2013.01); C12N 2810/405 (2013.01);
Abstract
The invention relates to a recombinant adenovirus nucleic acid wherein the gene encoding protein V and/or the gene encoding protein VII is placed under control of a heterologous promoter, to a recombinant adenovirus nucleic acid wherein the adenoviral nucleotide sequence is mutated in such a way that it is no longer capable of producing one or more of the coat proteins, to cellular vesicles filled with such adenoviral material, cells provided with such adenoviral material and to methods and use thereof.