The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 07, 2025
Filed:
Feb. 07, 2020
Astrazeneca Ab, Sodertalje, SE;
Scott Nathan Mlynarski, Waltham, MA (US);
Tyler Grebe, Waltham, MA (US);
Sameer Kawatkar, Waltham, MA (US);
Maurice Raymond Verschoyle Finlay, Cambridge, GB;
Iain Simpson, Cambridge, GB;
AstraZeneca AB, Sodertalje, SE;
Abstract
Disclosed are compounds of formula (Ib) or (Vc), or a pharmaceutically acceptable salt thereof, pharmaceutical compositions comprising compounds of formula (Ib) or (Vc) and methods of using the same for treating cancer, respiratory inflammatory disease, and inhibiting arginase; wherein Ris —H or —C(O)CH(R)NHR; and Ris selected from —H, —(C-C) alkyl and CHOR; Ris —H; or alternatively, Rand R, together with the atom to which they are attached, form a 5-membered heterocyclic ring; and Ris H or —CH.