The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 07, 2025
Filed:
Nov. 28, 2020
Lupin Limited, Mumbai, IN;
Sachin Sethi, Pune, IN;
Prathap Sreedharan Nair, Pune, IN;
Manojkumar Ramprasad Shukla, Pune, IN;
Milind Dattatraya Sindkhedkar, Pune, IN;
Venkata P. Palle, Pune, IN;
Rajender Kumar Kamboj, Pune, IN;
Samiron Phukan, Pune, IN;
Pradeep Rangrao Patil, Pune, IN;
Ganesh Kakade, Pune, IN;
Nilesh Raghunath Khedkar, Pune, IN;
Dagadu Dube, Pune, IN;
Vikas Sitaram Tambe, Pune, IN;
Sudhakar Maruti Balgude, Pune, IN;
Pradip Balu Wagh, Pune, IN;
LUPIN LIMITED, , IN;
Abstract
Disclosed are compounds of the general formula (I), its tautomeric form, its stereoisomer, its pharmaceutically acceptable salt, its polymorph, or solvate thereof, Formula (I) wherein, ring A, Rto R, X, Y, m, and n are as defined herein, for use as SOS1 inhibitors in the treatment of proliferative, infectious and RASopathy diseases or disorders. Also disclosed are methods of synthesizing the compound of formula I, pharmaceutical compositions containing the compound of formula I, method of treatment of proliferative, infectious and RASopathy diseases or disorder, for example, a cancer, by administering the said compound and combinations of the compound of formula I with other active ingredients.