The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 07, 2025

Filed:

Jul. 04, 2019
Applicant:

F.i.s.—fabbrica Italiana Sintetici S.p.a., Montecchio Maggiore, IT;

Inventors:

Paolo Stabile, Montecchio Maggiore, IT;

Floriana Semeraro, Montecchio Maggiore, IT;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 231/46 (2006.01); B01J 23/44 (2006.01); C07C 65/105 (2006.01); C07C 201/08 (2006.01); C07C 227/04 (2006.01);
U.S. Cl.
CPC ...
C07D 231/46 (2013.01); B01J 23/44 (2013.01); C07C 65/105 (2013.01); C07C 201/08 (2013.01); C07C 227/04 (2013.01); C07B 2200/13 (2013.01);
Abstract

Object of the present invention is an improved process for the preparation of key intermediates for the synthesis of Eltrombopag, passing through/using intermediate 5′-Chloro-2′-hydroxy[1,1′-biphenyl]-3-carboxylic acid alkaline metal salt of formula: wherein A is an alkaline metal.


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