The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 07, 2025
Filed:
Jan. 26, 2024
China Agricultural University, Beijing, CN;
Jianzhong Shen, Beijing, CN;
Kui Zhu, Beijing, CN;
Xiaoyu Li, Beijing, CN;
Kaixiang Zhou, Beijing, CN;
Changsi Mao, Beijing, CN;
Yawei Cai, Beijing, CN;
Jijun Kang, Beijing, CN;
Congming Wu, Beijing, CN;
Xingyuan Cao, Beijing, CN;
Dejun Liu, Beijing, CN;
CHINA AGRICULTURAL UNIVERSITY, Beijing, CN;
Abstract
A compound with broad-spectrum antibacterial activity and its antibacterial composition are provided. The compound with broad-spectrum antibacterial activity has formula (I), which are antibacterial drug source compounds with a broad antibacterial spectrum, good antibacterial activity, suitable in vivo pharmacokinetics, and significant in vivo therapeutic effects. Preferred compound BAB159 has good antibacterial activity against, and, which is comparable or better than the listed drugs. The combination of preferred compound BAB159 and polymyxin E exhibits significantly enhanced synergistic antibacterial activity, especially against multidrug-resistant strains.