The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 07, 2025
Filed:
Oct. 24, 2019
Applicant:
Richter Gedeon Nyrt, Budapest, HU;
Inventors:
Assignee:
RICHTER GEDEON NYRT, Budapest, HU;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 47/18 (2017.01); A61K 9/00 (2006.01); A61K 47/26 (2006.01); C07K 16/28 (2006.01);
U.S. Cl.
CPC ...
A61K 47/183 (2013.01); A61K 9/0019 (2013.01); A61K 47/26 (2013.01); C07K 16/2866 (2013.01);
Abstract
Provided are an aqueous pharmaceutical formulation comprising an antibody specific to the receptor of interleukin (IL)-6 (for example, Tocilizumab) and an effective amount of histidine for stabilizing the antibody. Said histidine is present in the aqueous pharmaceutical formulation at a concentration of 50 mM to 200 mM so as to achieve the stabilizing effect.