The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 07, 2025
Filed:
Mar. 28, 2014
Biomed Valley Discoveries, Inc., Kansas City, MO (US);
The Johns Hopkins University, Baltimore, MD (US);
Saurabh Saha, Wellesley Hills, MA (US);
Shibin Zhou, Owings Mills, MD (US);
Bert Vogelstein, Baltimore, MD (US);
Kenneth W. Kinzler, Bel Air, MD (US);
Biomed Valley Discoveries, Inc., Kansas City, MO (US);
Abstract
The present invention provides, inter alia, methods for treating or ameliorating an effect of a solid tumor present in a non-human animal. These methods include administering intratumorally to the non-human animal a unit dose of, preferablyNT, colony forming units (CFUs), which contains about 1×106-1×1010 CFUs suspended in a pharmaceutically acceptable carrier or solution. Methods for debulking a solid tumor present in a non-human animal, a method for microscopically precise excision of tumor cells in a non-human animal, methods for treating or ameliorating an effect of a solid tumor that has metastasized to one or more sites in a non-human animal, methods for ablating a solid tumor present in a non-human animal, unit doses of, preferablyNT, CFUs, and kits for treating or ameliorating an effect of a solid tumor present in a non-human animal are also provided.