The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 07, 2025
Filed:
Apr. 28, 2023
Applicant:
Prime Merger Sub, Llc, Birmingham, AL (US);
Inventors:
Jeffrey S. White, Birchrunville, PA (US);
Robin R. Young, Beaverton, OR (US);
Assignee:
Prime Merger Sub, LLC, Birmingham, AL (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 35/50 (2015.01); A61K 38/57 (2006.01); A61L 27/36 (2006.01); A61L 27/54 (2006.01); A61K 9/00 (2006.01); A61K 47/36 (2006.01);
U.S. Cl.
CPC ...
A61K 35/50 (2013.01); A61K 38/57 (2013.01); A61L 27/3604 (2013.01); A61L 27/54 (2013.01); A61K 9/0019 (2013.01); A61K 47/36 (2013.01); A61L 2300/434 (2013.01); A61L 2430/24 (2013.01);
Abstract
Methods for treating joint diseases, disorders, and conditions, such as osteoarthritis, with a composition containing a therapeutically effective amount of tissue inhibitors of matrix metalloproteinases (TIMPs) are provided. The composition can contain TIMPs as part of amniotic fluid, or the TIMPs can be isolated from another source or recombinantly produced. The methods are particularly useful for treating osteoarthritis associated with degradation of articular cartilage by proteases. Also provided are methods of lubricating a joint, such as an osteoarthritic joint.