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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 12433918 B1

PDFFull Text
Date of Patent:
Oct. 07, 2025

Filed:

Apr. 28, 2023

Methods of treating joint disease, disorders, and conditions with tissue inhibitors of matrix metalloproteinase

Applicant:

Prime Merger Sub, Llc, Birmingham, AL (US);

Inventors:

Jeffrey S. White, Birchrunville, PA (US);

Robin R. Young, Beaverton, OR (US);

Assignee:

Prime Merger Sub, LLC, Birmingham, AL (US);

Attorneys:

C. Brandon Browning

Maynard Nexsen PC

Primary Examiner:

Erin M Bowers

Int. Cl.
CPC ...
A61K 35/50 (2015.01); A61K 38/57 (2006.01); A61L 27/36 (2006.01); A61L 27/54 (2006.01); A61K 9/00 (2006.01); A61K 47/36 (2006.01);
U.S. Cl.
CPC ...
A61K 35/50 (2013.01); A61K 38/57 (2013.01); A61L 27/3604 (2013.01); A61L 27/54 (2013.01); A61K 9/0019 (2013.01); A61K 47/36 (2013.01); A61L 2300/434 (2013.01); A61L 2430/24 (2013.01);
Abstract

Methods for treating joint diseases, disorders, and conditions, such as osteoarthritis, with a composition containing a therapeutically effective amount of tissue inhibitors of matrix metalloproteinases (TIMPs) are provided. The composition can contain TIMPs as part of amniotic fluid, or the TIMPs can be isolated from another source or recombinantly produced. The methods are particularly useful for treating osteoarthritis associated with degradation of articular cartilage by proteases. Also provided are methods of lubricating a joint, such as an osteoarthritic joint.

Find Patent Forward Citations

White, Jeffrey. (2025). Methods of treating joint disease, disorders, and conditions with tissue inhibitors of matrix metalloproteinase (U.S. Patent No. 12433918). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/12433918

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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