The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 07, 2025
Filed:
May. 13, 2022
Durect Corporation, Cupertino, CA (US);
Adrian Neil Verity, Helotis, TX (US);
Steven Halladay, Oro Valley, AZ (US);
Vaeling Miller, Sunnyvale, CA (US);
Peter Langecker, Monte Sereno, CA (US);
Dmitri Lissin, Redwood City, CA (US);
Andrew R. Miksztal, Palo Alto, CA (US);
Judy Joice, San Jose, CA (US);
Susan Autio, San Jose, CA (US);
Mark P. Davis, Middleton, WI (US);
Durect Corporation, Cupertino, CA (US);
Abstract
The present disclosure provides for methods of producing analgesia in a subject. In some cases, methods produce analgesia in a subject undergoing arthroscopic subacromial decompression surgery. The present disclosure also relates to improved sustained release drug delivery systems. In some cases, a composition comprises an active pharmaceutical agent; at least one of sucrose acetate isobutyrate and a polyorthoester; an organic solvent; and 2,6-dimethylaniline, wherein the 2,6-dimethylaniline is present at a level less than 500 ppm. In some cases, a composition comprises bupivacaine N-oxide at a level less than 1 wt %, based on weight of the composition. In some cases, a composition comprises metal present at a level less than 5 ppm. Dosage forms and methods are also provided.