The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 07, 2025

Filed:

Nov. 06, 2023
Applicant:

Nephrodi Therapeutics, Inc., Seattle, WA (US);

Inventors:

Jeff Sands, Atlanta, GA (US);

Janet Klein, Decatur, GA (US);

Ish Khanna, Alpharetta, GA (US);

Sivaram Pillarisetti, Norcross, GA (US);

Assignee:

NephroDI Therapeutics, Inc., Seattle, WA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/19 (2006.01); A61K 9/00 (2006.01); A61K 31/16 (2006.01); A61K 31/194 (2006.01); A61K 33/00 (2006.01); A61P 3/10 (2006.01); C07C 61/00 (2006.01);
U.S. Cl.
CPC ...
A61K 31/16 (2013.01); A61K 9/0095 (2013.01); A61K 31/194 (2013.01); A61K 33/00 (2013.01); A61P 3/10 (2018.01); A61K 9/0053 (2013.01);
Abstract

In certain embodiments, this disclosure relates to methods of treating or preventing nephrogenic diabetes insipidus comprising administering an effective amount of compounds of the class of alkyl carboxylic acids, such as 1,1'-(decane-1,10-diyl)bis(cyclopropane-1-carboxylic acid), pharmaceutical salts or derivatives thereof, and the class of alkyl amides, such as 1,1′-(dodecane-1,12-diyl)bis(cyclopropane-1-carboxamide), pharmaceutical salts or derivatives thereof, as described herein, to a subject in need thereof. In certain embodiments, the subject has been diagnosed with nephrogenic diabetes insipidus.


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