The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 07, 2025

Filed:

Aug. 07, 2023
Applicant:

Epizon Pharma, Inc., New York, NY (US);

Inventors:

James A. Tumlin, Lawrenceville, GA (US);

Paul L. Darke, Hingham, MA (US);

John M. Rudey, New York, NY (US);

Assignee:

Epizon Pharma, Inc., New York, NY (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/122 (2006.01); A61K 31/047 (2006.01); A61K 31/22 (2006.01); A61K 31/366 (2006.01); A61K 31/40 (2006.01); A61K 31/405 (2006.01); A61K 31/47 (2006.01); A61K 31/505 (2006.01); A61P 3/14 (2006.01); A61P 13/12 (2006.01);
U.S. Cl.
CPC ...
A61K 31/122 (2013.01); A61K 31/047 (2013.01); A61K 31/22 (2013.01); A61K 31/366 (2013.01); A61K 31/40 (2013.01); A61K 31/405 (2013.01); A61K 31/47 (2013.01); A61K 31/505 (2013.01); A61P 3/14 (2018.01); A61P 13/12 (2018.01);
Abstract

The invention provides methods and compositions for preventing or treating (e.g., slowing the progression of, arresting, and/or reversing) calciphylaxis in a subject in need thereof and, more particularly, the invention relates to methods of using menaquinone-7 (MK-7) and/or menaquinol-7 (MKH2-7) for preventing or treating calciphylaxis in a subject with one or more of the following: diabetes, chronic kidney disease, end stage renal failure, and COPD or a subject undergoing hemodialysis and/or receiving anticoagulant therapy and/or statin therapy.


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