The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 07, 2025

Filed:

Feb. 18, 2022
Applicant:

Case Western Reserve University, Cleveland, OH (US);

Inventors:

Nicole F. Steinmetz, San Diego, CA (US);

Jonathan Pokorski, San Diego, CA (US);

Assignee:

CASE WESTERN RESERVE UNIVERSITY, Cleveland, OH (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 9/16 (2006.01); A61K 38/00 (2006.01); A61K 39/00 (2006.01); C08K 11/00 (2006.01);
U.S. Cl.
CPC ...
A61K 9/1647 (2013.01); A61K 39/00 (2013.01); C08K 11/00 (2013.01); A61K 38/00 (2013.01); A61K 2039/54 (2013.01); C08K 2201/011 (2013.01);
Abstract

A construct includes a melt processed blend of a biodegradable polymer and viral nanoparticles. The viral nanoparticles are encapsulated within a biodegradable polymer matrix of the biodegradable polymer. The viral nanoparticles include a plurality of immunogenic peptides conjugated to the viral nanoparticles. The construct upon administration to a subject providing sustained release of the viral nanoparticles and conjugated immunogenic peptides from the matrix to the subject. The released viral nanoparticles and conjugated immunogenic peptides eliciting an immunogenic response in the subject.


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