The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 30, 2025
Filed:
Nov. 11, 2020
Applicant:
Seven Bridges Genomics Inc., Charlestown, MA (US);
Inventor:
Deniz Kural, Charlestown, MA (US);
Assignee:
Seven Bridges Genomics Inc., Charlestown, MA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G16B 30/10 (2019.01); G16B 20/20 (2019.01); G16B 30/00 (2019.01); G16B 30/20 (2019.01);
U.S. Cl.
CPC ...
G16B 30/10 (2019.02); G16B 30/00 (2019.02); G16B 20/20 (2019.02); G16B 30/20 (2019.02);
Abstract
The invention generally relates to genomic studies and specifically to improved methods for read mapping using identified nucleotides at known locations. The invention provides methods of using identified nucleotides at known places in a genome to guide the analysis of sequence reads from that genome by excluding potential mappings or assemblies that are not congruent with the identified nucleotides. Information about a plurality of SNPs in the subject's genome is used to identify candidate paths through a genomic directed acyclic graph (DAG). Sequence reads are mapped to the candidate paths.