The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 30, 2025
Filed:
Mar. 08, 2023
Illumina, Inc., San Diego, CA (US);
Tarun Kumar Khurana, Fremont, CA (US);
Yir-Shyuan Wu, Fremont, CA (US);
Xi-Jun Chen, Fremont, CA (US);
Filiz Gorpe-Yasar, Fremont, CA (US);
Yan-You Lin, Fremont, CA (US);
Victoria Popic, Fremont, CA (US);
Erich B. Jaeger, Fremont, CA (US);
Mostafa Ronaghi, Fremont, CA (US);
Illumina, Inc., San Diego, CA (US);
Abstract
Implementations of a method for seeding sequence libraries on a surface of a sequencing flow cell that allow for spatial segregation of the libraries on the surface are provided. The spatial segregation can be used to index sequence reads from individual sequencing libraries to increase efficiency of subsequent data analysis. In some examples, hydrogel beads containing encapsulated sequencing libraries are captured on a sequencing flow cell and degraded in the presence of a liquid diffusion barrier to allow for the spatial segregation and seeding of the sequencing libraries on the surface of the flow cell. Additionally, examples of systems, methods and compositions are provided relating to flow cell devices configured for nucleic acid library preparation and single cell sequencing. Some examples include flow cell devices having a hydrogel with genetic material disposed therein, and which is retained within the hydrogel during nucleic acid processing.