The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 30, 2025
Filed:
Dec. 14, 2020
Albert-ludwigs-universitaet Freiburg, Freiburg, DE;
Toni Cathomen, Freiburg, DE;
Philipp Wolf, Sexau, DE;
Jamal Alzubi, Freiburg, DE;
Susanne Schultze-Seemann, Merzhausen, DE;
Irina Kuckuck, Freiburg, DE;
Albert-Ludwigs-Universitaet Freiburg, Freiburg, DE;
Abstract
The present invention relates to a novel chimeric antigen receptor (CAR) comprising an antigen-binding fragment which binds specifically to PSMA antigen, and a method of manufacturing high-quality CAR T cell products by transfection and/or transduction of T cells therewith, which allows to effectively treat tumors in vivo alone or in combination with pharmaceutical drugs, such chemotherapies, biopharmaceutical drugs, such as antibodies, or small-molecule drugs, such as protein kinase inhibitors.