The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 30, 2025
Filed:
Dec. 05, 2019
Applicant:
Alexion Pharmaceuticals, Inc., Boston, MA (US);
Inventors:
Jeffrey William Hunter, Wallingford, CT (US);
Julian Chandler, Old Lyme, CT (US);
Keith Bouchard, Unionville, CT (US);
Andre Marozsan, Killingworth, CT (US);
Patricia Bento, Plantsville, CT (US);
Anjli Kukreja, Fairfield, CT (US);
Assignee:
Alexion Pharmaceuticals, Inc., Boston, MA (US);
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/28 (2006.01); A61K 31/59 (2006.01); A61K 33/06 (2006.01); A61K 39/00 (2006.01); A61K 39/395 (2006.01); A61P 19/10 (2006.01); G01N 33/573 (2006.01);
U.S. Cl.
CPC ...
C07K 16/2863 (2013.01); A61K 31/59 (2013.01); A61K 33/06 (2013.01); A61K 39/3955 (2013.01); A61P 19/10 (2018.01); G01N 33/573 (2013.01); A61K 2039/505 (2013.01); C07K 2317/24 (2013.01); C07K 2317/92 (2013.01); G01N 2333/912 (2013.01);
Abstract
Provided herein are antibodies that bind to activin receptor-like kinase 2 (ALK2) and are useful for treating bone disorders, such as those involving reduced bone mineral density and bone mineralization defects, and promoting bone growth. Also provided are polynucleotides encoding the antibodies, vectors comprising the polynucleotides, and cells that produce the antibodies.