The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 30, 2025
Filed:
Jul. 01, 2021
Applicant:
Op-t Llc, Denver, CO (US);
Inventors:
David H. Wagner, Jr., Denver, CO (US);
Martin G. Yussman, Denver, CO (US);
Charles W. Henry, Denver, CO (US);
Assignee:
OP-T LLC, Aurora, CO (US);
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 14/705 (2006.01); A61K 38/08 (2019.01); A61K 38/17 (2006.01); A61K 38/19 (2006.01); A61K 40/42 (2025.01); A61K 38/10 (2006.01);
U.S. Cl.
CPC ...
C07K 14/70575 (2013.01); A61K 38/191 (2013.01); A61K 38/08 (2013.01); A61K 38/10 (2013.01); A61K 38/1774 (2013.01); A61K 40/4215 (2025.01);
Abstract
The present disclosure provides, among other things, small peptides that are capable of interacting with CD40, thereby interfering with the ability of CD40 to interact with CD154, which impacts, e.g., inflammation and atherosclerosis. The present disclosure further provides use of such peptides in the treatment of, e.g., type 2 diabetes and auto-inflammatory disease. In particular, small peptides that are capable of interacting with CD40, thereby interfering with the ability of CD40 to interact with CD154, impact inflammation and type 2 diabetes.