The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 30, 2025
Filed:
Feb. 01, 2022
Triad National Security, Llc, Los Alamos, NM (US);
William M. Fischer, Los Alamos, NM (US);
Peter T. Hraber, Los Alamos, NM (US);
Triad National Security, LLC, Los Alamos, NM (US);
Abstract
Synthetic immunogenic polypeptides based on a curated set of natural alphavirus structural protein sequences are described. The polypeptides were computationally designed to provide optimal coverage of potential immunogenic epitopes of wild-type alphaviruses, including isolates of Venezuelan equine encephalitis virus, Western equine encephalitis virus, Eastern equine encephalitis virus and Chikungunya virus. Sets of immunogenic polypeptides, as well as nucleic acid molecules and vectors encoding the immunogenic polypeptides are also described. The disclosed compositions can be used to elicit an immune response against alphaviruses in a subject.