The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 30, 2025
Filed:
Jan. 08, 2021
Jiangsu Hengrui Medicine Co., Ltd., Lianyungang, CN;
Shanghai Hengrui Pharmaceutical Co., Ltd., Shanghai, CN;
Fanglong Yang, Shanghai, CN;
Xing Fan, Shanghai, CN;
Jingjing Yan, Shanghai, CN;
Xiqian Zhang, Shanghai, CN;
Feng He, Shanghai, CN;
Weikang Tao, Shanghai, CN;
JIANGSU HENGRUI MEDICINE CO., LTD., Lianyungang, CN;
SHANGHAI HENGRUI PHARMACEUTICAL CO., LTD., Shanghai, CN;
Abstract
The present disclosure relates to a tricyclic tetrahydroisoquinoline derivative, a preparation method therefor and an application thereof in medicine. In particular, the present disclosure relates to a tricyclic tetrahydroisoquinoline derivative represented by general formula (I), a preparation method therefor and a pharmaceutical composition comprising said derivative, a use thereof as an estrogen receptor modulator, and a use thereof in preparing a drug for treating estrogen receptor-mediated or dependent diseases or disorders. The substituents in general formula (I) are the same as those defined in the description.