The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 30, 2025

Filed:

Jul. 27, 2020
Applicant:

The Brigham and Women's Hospital, Inc., Boston, MA (US);

Inventors:

Mihaela Gadjeva, Cambridge, MA (US);

Nikolay E. Nifantiev, Moscow, RU;

Igor V. Zavarzin, Moscow, RU;

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 471/04 (2006.01); A61K 31/437 (2006.01); A61K 31/505 (2006.01); A61P 33/06 (2006.01);
U.S. Cl.
CPC ...
C07D 471/04 (2013.01); A61K 31/437 (2013.01); A61K 31/505 (2013.01); A61P 33/06 (2018.01);
Abstract

The present application provides a compound of Formula (I): [Formula I] or a pharmaceutically acceptable salt thereof, wherein R, R, R, R, R, R, W, L, R, and Rare as described herein. Pharmaceutical compositions including these compounds and methods of using these compounds for treating parasitic infections (e.g., malaria), cancer, cardiovascular diseases, neurological diseases, inflammatory diseases, neuropathic pain, and other conditions are also disclosed herein.


Find Patent Forward Citations

Gadjeva, Mihaela. (2025). Inhibitors of macrophage migration inhibitory factor (U.S. Patent No. 12428417). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/12428417

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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