The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 30, 2025
Filed:
Jan. 28, 2022
Applicants:
The Brigham and Women's Hospital, Inc., Boston, MA (US);
Beth Israel Deaconess Medical Center, Inc., Boston, MA (US);
Inventors:
Mark Feinberg, Newton, MA (US);
Santosh A. Khedkar, Lexington, MA (US);
Assignees:
The Brigham and Women's Hospital, Inc., Boston, MA (US);
Beth Israel Deaconess Medical Center, Inc., Boston, MA (US);
Primary Examiner:
Int. Cl.
CPC ...
C07D 409/12 (2006.01); C07C 39/15 (2006.01); C07C 49/84 (2006.01); C07C 205/45 (2006.01); C07C 217/48 (2006.01); C07C 251/86 (2006.01); C07D 207/44 (2006.01); C07D 239/38 (2006.01); C07D 239/52 (2006.01); C07D 311/62 (2006.01);
U.S. Cl.
CPC ...
C07D 409/12 (2013.01); C07C 39/15 (2013.01); C07C 49/84 (2013.01); C07C 205/45 (2013.01); C07C 217/48 (2013.01); C07C 251/86 (2013.01); C07D 207/44 (2013.01); C07D 239/38 (2013.01); C07D 239/52 (2013.01); C07D 311/62 (2013.01);
Abstract
The invention relates to compositions and methods for inhibiting Krüppel-like Factor 10 (KLF10) for modulation of T regulatory cells and cancer immunotherapy.