The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 30, 2025

Filed:

Jun. 24, 2022
Applicant:

Crystal Pharmaceutical (Suzhou) Co., Ltd., Suzhou, CN;

Inventors:

Minhua Chen, Suzhou, CN;

Xingjuan Chang, Suzhou, CN;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 403/12 (2006.01);
U.S. Cl.
CPC ...
C07D 403/12 (2013.01); C07B 2200/13 (2013.01);
Abstract

Novel crystalline forms of Resmetirom (Referred to as “Compound I”), and preparation methods thereof, pharmaceutical compositions containing the crystalline forms, and uses of the crystalline forms for preparing THR-β selective agonist drugs and drugs for treating NASH and HeFH. Compared with prior arts, the provided crystalline forms of Compound I have one or more improved properties, which is of great value to the optimization and development of the drugs containing Compound I.


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