The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 30, 2025

Filed:

Mar. 27, 2024
Applicant:

Yuhan Corporation, Seoul, KR;

Inventors:

Sang Ho Oh, Gyeonggi-do, KR;

Jong Gyun Kim, Gyeonggi-do, KR;

Se-Woong Oh, Gyeonggi-do, KR;

Tae Dong Han, Gyeonggi-do, KR;

Soo Yong Chung, Gyeonggi-do, KR;

Seong Ran Lee, Gyeonggi-do, KR;

Kyeong Bae Kim, Seoul, KR;

Young Sung Lee, Seoul, KR;

Woo Seob Shin, Gyeonggi-do, KR;

Hyun Ju, Gyeonggi-do, KR;

Jeong Ki Kang, Gyeonggi-do, KR;

Su Min Park, Chungcheongbuk-do, KR;

Dong Kyun Kim, Gyeonggi-do, KR;

Assignee:

Yuhan Corporation, Seoul, KR;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 403/04 (2006.01); A61K 31/5377 (2006.01); A61P 35/00 (2006.01); C07C 303/22 (2006.01); C07C 309/04 (2006.01); C07D 413/14 (2006.01);
U.S. Cl.
CPC ...
C07D 403/04 (2013.01); C07C 303/22 (2013.01); C07C 309/04 (2013.01); C07B 2200/13 (2013.01);
Abstract

The present invention relates to novel mesylate salt of N-(5-(4-(4-((dimethylamino)methyl)-3-phenyl-1H-pyrazol-1-yl)pyrimidine-2-ylamino)-4-methoxy-2-morpholinophenyl)acrylamide, a novel crystalline form thereof, and a process for preparing the same. More specifically, the present invention relates to mesylate salt of N-(5-(4-(4-((dimethylamino)methyl)-3-phenyl-1H-pyrazol-1-yl)pyrimidine-2-ylamino)-4-methoxy-2-morpholinophenyl)acrylamide, which is excellent in stability, solubility, and bioavailability when it is administered not only alone but also in combination with other drugs and which has a high purity, a crystalline form thereof, and a process for preparing the same.


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