The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 30, 2025

Filed:

May. 19, 2022
Applicant:

Yongfu LI, Corvallis, OR (US);

Inventor:

Yongfu Li, Corvallis, OR (US);

Assignee:

Brotide Core, LLC, Corvallis, OR (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 471/04 (2006.01); C07D 251/54 (2006.01); C07K 1/04 (2006.01);
U.S. Cl.
CPC ...
C07D 251/54 (2013.01); C07D 471/04 (2013.01); C07K 1/042 (2013.01);
Abstract

Disclosed is a lipophilic agent comprising a triazine core having lipophilic groups for organic synthesis. The lipophilic agent soluble in one system of solvent(s) wherein the lipophilic agent is participated in a chemical reaction but insoluble by adding a miscible poor solvent to change solution composition after the reaction completes. The lipophilic agent facilitates process improvement wherein practical operation only involves mixing with reactants in solution followed by precipitating with change of solution composition followed by filtering to obtain the precipitated solid, simplifying the purification by isolating the desired solid. The operation is reproducible along the progress in a multi-step synthesis, allowing pure intermediates and pure product as a solid to be rapidly obtained with ease and certainty. This invention can thus accelerate research and development of pharmaceutical biomolecules, representing a tremendous step forward for boosting productivity and greening chemical industry.


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