The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 30, 2025
Filed:
Jul. 25, 2019
Asymchem Life Science (Tianjin) Co., Ltd, Tianjin, CN;
Hao Hong, Morrisville, NC (US);
Jiangping Lu, Tianjin, CN;
Jian Tao, Tianjin, CN;
Yan Zhang, Tianjin, CN;
Fan Wang, Tianjin, CN;
Gonzalez Miguel, Morrisville, NC (US);
ASYMCHEM LIFE SCIENCE (TIANJIN) CO., LTD, Tianjin, CN;
Abstract
The present disclosure provides a preparation method for metformin hydrochloride. The preparation method includes: microwave heating raw materials containing dicyandiamide and dimethylamine hydrochloride, and reacting the two at 100° C. to 160° C. to obtain a product system containing metformin hydrochloride. Microwave heating is adopted to heat the dicyandiamide and the dimethylamine hydrochloride. Compared with a conventional heating mode that requires heat to be gradually transferred from the outside to the inside, microwave heating can directly heat each part inside the reactant, which can make the internal temperature of the reactant more uniform, thereby reducing the generation of impurities.